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9 Brain-Protective Nutrients for Dogs Experiencing Cognitive Decline

by Doggone Well Staff
April 22, 2025
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9 Brain-Protective Nutrients for Dogs Experiencing Cognitive Decline
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MidJourney



Just like humans, dogs can experience cognitive decline as they get older. Symptoms like disorientation, disrupted sleep patterns, and reduced interest in their surroundings may be signs of canine cognitive dysfunction. While there’s no cure, research shows that specific nutrients can support brain health and potentially slow the progression of mental decline in senior dogs. Here are nine nutrients that may help keep your dog’s brain sharp and active.

Omega-3 Fatty Acids

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Omega-3s, especially DHA (docosahexaenoic acid), are essential for brain function. DHA helps support cell membrane health in the brain and is known to promote learning and memory. One of the best sources for dogs is fish oil. Supplementing with iHeartDogs Norweigan High Omega-3 Salmon Oil (on Amazon) can support cognitive function and help reduce inflammation that may contribute to mental decline.

Vitamin E

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Vitamin E acts as a powerful antioxidant that helps protect brain cells from oxidative damage. It’s often included in multivitamins designed for senior dogs. The Senior Dog 24-in-1 Multivitamin (on Amazon) contains Vitamin E along with other nutrients to support your dog’s heart, immune system, and cognition.



B Vitamins

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B vitamins like B6, B12, and folic acid are involved in nerve function and energy metabolism. Deficiencies in these vitamins can lead to confusion and cognitive decline. You’ll find a balanced blend of B vitamins in the Senior Dog 24-in-1 Multivitamin (on Amazon), making it an easy way to support brain and overall health.

Antioxidants

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Antioxidants help neutralize free radicals that can damage brain tissue. A variety of plant-based antioxidants—like blueberries, spinach, and kale—can be found in Super Greens Vitamin and Mineral Powder for Dogs (on Amazon). This blend offers a convenient way to add antioxidant-rich greens to your dog’s meals.

Coenzyme Q10

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CoQ10 is an antioxidant that also plays a key role in energy production in cells, including those in the brain. It may help improve alertness and reduce symptoms of canine cognitive dysfunction. It’s one of the many ingredients in Senior 7 Anti-Aging Support for Dogs with Antioxidants (on Amazon), a supplement designed specifically for older dogs.



L-Carnitine

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This amino acid supports brain metabolism and can help improve memory and focus in older dogs. It works by helping cells use fat for energy, which is especially useful for the high-energy demands of brain cells. You can find it in the Senior 7 Anti-Aging Support for Dogs with Antioxidants (on Amazon), which includes a combination of brain-friendly nutrients.

Alpha Lipoic Acid

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Alpha lipoic acid is another potent antioxidant that also regenerates other antioxidants like Vitamin C and E. It supports mitochondrial function and may help slow cognitive aging. The Senior 7 Anti-Aging Support for Dogs with Antioxidants (on Amazon) includes alpha lipoic acid as part of its brain and longevity formula.

Phosphatidylserine

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This phospholipid supports communication between brain cells and is known to improve attention, memory, and learning in aging dogs. It is commonly included in high-quality senior dog supplements such as the Senior 7 Anti-Aging Support for Dogs with Antioxidants (on Amazon).



Medicinal Mushrooms

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Certain medicinal mushrooms, such as turkey tail, have compounds that support immune health and may protect against cognitive decline. Turkey Tail Mushrooms for Dog Lumps, Bumps and Immune Support (on Amazon) are rich in polysaccharides that help fight oxidative stress and inflammation—both contributors to brain aging.

Give Your Dog’s Brain a Fighting Chance

9 Brain-Protective Nutrients for Dogs Experiencing Cognitive DeclineMidJourney

Aging doesn’t have to mean losing mental sharpness. With the right nutritional support, you can give your dog a better chance at maintaining a lively and aware mind well into their senior years. Adding brain-supportive supplements to their daily routine, along with enrichment and exercise, may help them stay happier and more connected to you. Disclosure: As an Amazon Associate, iHeartDogs earns from qualifying purchases.





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