Can LSD Therapy Calm Anxious Dogs? First-Of-Its-Kind Study Uncovers New Possibilities

A groundbreaking study conducted by researchers from Spain’s Universidad de las Palmas de Gran Canaria has shown that low-dose LSD may provide a safe and effective treatment for dogs suffering from anxiety. This independent study, published in Veterinary Research Communications, is the first of its kind to explore the effects of the psychedelic on a canine patient, revealing promising results with no adverse effects.

The case study focused on a 13-year-old dog named Lola, who struggles with severe separation anxiety. Researchers administered a single dose of 1cp-LSD, a derivative of LSD and observed the dog’s behavior over five hours. Throughout the study, Lola was exposed to anxiety-inducing situations, such as her owners leaving the house, a scenario known to trigger distress in the dog.

Findings And Observations

Though there was no significant change in behavior during the first two hours, researchers noted that Lola appeared calmer afterward. “A significant change in the animal's behavior was observed with no signs or mild signs of anxiety,” the study stated.

Results revealed that low-dose LSD may help dogs cope with anxiety without triggering a psychedelic experience. “The trial concluded without any adverse effects on the animal. The patient did not show signs of having a psychedelic experience,” the researchers confirmed. At key moments, such as when the owner left the house, Lola remained calm, showing no signs of her usual anxious behaviors like barking or vocalization. The duration of the experience was comparable to that reported in humans, with the peak effect observed at 2–3 h and a gradual return to baseline from 5 hours onwards. 

The implications of this study are significant given the prevalence of anxiety in pets. Traditional treatments, such as anti-depressants and benzodiazepines, are known to have limited efficacy and often come with concerning side effects. With approximately 20 percent of dogs experiencing anxiety, the potential for alternative treatments like 1cp-LSD could transform veterinary care.

Alternative Therapies For Animals Gaining Ground

This study adds to the growing interest in using alternative therapies, including psychedelics and cannabis, to treat pets. Earlier this year, the National Animal Supplement Council promoted research indicating that CBD is “safe for long-term use” in dogs. Studies have shown that cannabis can alleviate conditions such as anxiety, skin diseases, and even arthritis in canines.

With CBD already being explored as a treatment option, the safe use of 1cp-LSD could pave the way for further studies into psychedelics as a veterinary treatment. The research team noted that while these initial results are promising, more studies are needed to fully understand the potential of microdosing LSD in treating separation-related behavioral issues in dogs.

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